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KMID : 0894319970060010137
Dongguk Journal of the Institute of Oriental Medicine
1997 Volume.6 No. 1 p.137 ~ p.149
Effect of Kojinyumja(ͳòØëæí­) on Galactosamiine Induced hepatoxicity in Rats






Abstract
The purpose of this study is to observe the protective effect of Kojinyumja on serum reaction and hepatic tissue in galactosamine treated rats.
In this study, the experimental rats divided four group(Normal group, Control group, Sample A group, and Sample B group) :
Under the same condition, normal and control group were administered water, sample A, B group were administered Kojinyumja for 8days. And then, both control group and Sample B group were injected to abdomen with galactosamine for lday.
The rates of of glutathione, lipid peroxide, GOT, GPT, ¥ã-GTP, ALP, LDH, and contents of bile acid level were measured. The results are as follows :
The glutathione rate significantly increased in sample group, the others (lipid peroxide, GOT, GPT, ¥ã-GTP, ALP, LDH, bile acid) significantly decreased in sample group.
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